News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
FeaturedMedications
Wellbutrin Dosage: SR, XL, and the 450 mg Ceiling
Wellbutrin dosing depends on the version you take. See typical SR and XL doses, why 450 mg a day is the ceiling, and how seizure risk shapes every step up.
November 4, 2026Wellbutrin (Bupropion)Wellbutrin DosageWellbutrin XLBupropion Seizure RiskAntidepressant Dose Adjustment
MedicationsNovember 3, 2026
Wellbutrin SR vs XL: Same Medicine, Different Daily Rhythm
Wellbutrin SR is taken twice a day and XL once. Compare doses, side effects, seizure limits, and switching rules from the FDA labels to see which fits you.
Wellbutrin (Bupropion)Wellbutrin XLWellbutrin SR vs XLWellbutrin Side Effects
MedicationsSeptember 17, 2026
Wellbutrin and Weight: What the Clinical Evidence Shows
Wellbutrin is one of the few antidepressants linked to weight loss rather than weight gain. Here is what the mechanism and the clinical trial data actually show.
Wellbutrin and WeightBupropion Weight LossAntidepressant Weight ChangesWellbutrin XL