News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
Cymbalta Side Effects: First 2 Weeks vs Long Term
Cymbalta's early side effects and its long-term profile are not the same list. Here's which effects fade, which persist, and which get reported most to prescribers.
Guanfacine Side Effects: Sedation Timeline
Guanfacine's most common side effect is sedation, and it usually follows a predictable curve. Here's why tiredness peaks early and what fades within a few weeks.
Hydroxyzine Side Effects and Next-Day Grogginess
Hydroxyzine's sedation curve explains why grogginess can linger into the next morning, and how tolerance changes the picture over time.
Strattera Side Effects in the First Month: What to Expect
Strattera side effects follow a slower, different timeline than stimulants. Here's the appetite, sleep, and heart-rate pattern for the first month, and when to call your prescriber.
Trintellix Side Effects: Nausea Timeline
Nausea is Trintellix's signature side effect. Here's why it peaks in week one, when it typically fades, and what to do if it does not.
AI Medication Tracking: The Patterns a Quarterly Visit Will Never See
AI medication tracking captures what quarterly appointments cannot: the clinical patterns between visits that actually drive better prescribing decisions.
How to Know If Your Antidepressant Is Working When Your Mood Still Feels Off
Mood is often the last symptom to improve on an antidepressant. Here is what to actually watch for in the first 8 weeks and what early response really looks like.
Antidepressant Prescribing Online: What Patterns Your Care Team Is Tracking
When you start an antidepressant online, your care team watches for far more than side effects. Here are the clinical patterns that drive good prescribing decisions over time.
Side Effect Tracker: The 5 Categories Patients Most Often Forget to Log
Most patients track physical side effects. The five categories that actually drive treatment decisions are the ones nobody asks about.
Trazodone Side Effects: The Daytime Effects Patients Don't Realize Are Reportable
Morning grogginess, dizziness when standing, and cognitive fog from trazodone are rarely reported. Here's what qualifies as a reportable side effect and why it changes your treatment.
Zoloft Side Effects in the First 2 Weeks vs Long-Term: Knowing the Difference
Nausea and insomnia from Zoloft often resolve. Sexual side effects usually do not. Here's how to tell which side effects will pass and which need clinical attention.
Abilify Side Effects: What Patients Should Track Monthly
Most people on Abilify see their prescriber quarterly. Akathisia, compulsive behaviors, and early metabolic shifts show up in weeks. Here is what to track and when to report it.