News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
TMS Therapy Cost in 2026: What You Actually Pay
TMS pricing looks alarming until insurance enters the picture. Here's how the real math works, from per-session cost to what Medicare and private plans require.
Does TMS Therapy Work? What the Research Actually Shows
TMS response rates, how long benefits last, and how it compares to switching medications or ECT. The honest numbers behind transcranial magnetic stimulation.
Treatment-Resistant Depression Options: Beyond Standard Antidepressants
When two or more antidepressants fail at adequate dose and duration, TRD-specific options open up. Here is what the clinical evidence says about TMS, esketamine, ECT, MAOIs, and augmentation.
What Is TMS Therapy? Everything You Need to Know About Brain Stimulation for Depression
TMS therapy uses magnetic pulses to stimulate the brain regions that regulate mood. FDA-cleared since 2008, it is most often used for depression that hasn't responded to antidepressants.
Antidepressant Not Working After 8 Weeks: A Doctor-Reviewed Decision Path
Eight weeks on an antidepressant with no response is a clinical signal, not a dead end. Here is the doctor-reviewed decision path for what happens next.
Can AI Help With Medication Management for Treatment-Resistant Depression?
If two antidepressants have not worked, AI-assisted medication management may close the monitoring gap. Here is what the clinical evidence shows.
Antidepressant Not Working? 3 Patterns to Check Before You Switch
Before switching antidepressants, three clinical patterns explain most cases of apparent treatment failure. Here is how to check each one before making any changes.
Psychiatric Medication Management Online for Treatment-Resistant Patients
If you have tried two antidepressants without lasting relief, you may not have a treatment-resistant brain. You may have an under-evaluated treatment history. Here is what that difference means.