News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
Antidepressant Not Working After 8 Weeks: A Doctor-Reviewed Decision Path
Eight weeks on an antidepressant with no response is a clinical signal, not a dead end. Here is the doctor-reviewed decision path for what happens next.
Can AI Help With Medication Management for Treatment-Resistant Depression?
If two antidepressants have not worked, AI-assisted medication management may close the monitoring gap. Here is what the clinical evidence shows.
Antidepressant Not Working? 3 Patterns to Check Before You Switch
Before switching antidepressants, three clinical patterns explain most cases of apparent treatment failure. Here is how to check each one before making any changes.
Psychiatric Medication Management Online for Treatment-Resistant Patients
If you have tried two antidepressants without lasting relief, you may not have a treatment-resistant brain. You may have an under-evaluated treatment history. Here is what that difference means.