News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
How Long Does Zoloft Take to Work? A Week-by-Week Timeline
Zoloft can ease anxiety and sleep before low mood lifts. See what changes in weeks 1 to 12, when to check in early, and why week 8 is the real checkpoint.
How Long Does Prozac Take to Work? Steady State to Week 8
Prozac can start helping in 1 to 2 weeks, but it takes 4 to 5 weeks to reach steady state. Here's what its long half-life means and why week 8 matters.
SSRI Medications Compared: A Side-by-Side Look at the Major Options
All six major SSRIs work through the same mechanism but differ significantly in half-life, drug interactions, side effect profiles, and discontinuation risk. Here is a clinical comparison.
Antidepressant Prescribing Online: What Patterns Your Care Team Is Tracking
When you start an antidepressant online, your care team watches for far more than side effects. Here are the clinical patterns that drive good prescribing decisions over time.
Beta Blockers vs SSRIs for Anxiety: When to Use Each
Beta blockers work in 30 minutes. SSRIs take weeks. They treat different aspects of anxiety. Here is the clinical framework for when each is the right choice.
Anxiety Medication Management: How a Daily Check-In Changes the Conversation
Most people stop anxiety medication within six months, not because it fails, but because no one is checking in. Here is how daily monitoring changes that.