News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
What Is a Mental Status Exam? What Psychiatrists Look For
A mental status exam is psychiatry's version of a physical exam. Here is what it covers, why each part matters, and what it means for your diagnosis.
The Genetic Factors of Depression: What Your DNA Tells You
Depression is not caused by one broken gene. Here is what twin studies, large genetic studies, and decades of research actually show about DNA and depression risk.
What Causes Treatment-Resistant Depression? Biology and Blind Spots
If two antidepressants haven't helped, something specific may be in the way. Learn the biological and practical causes of treatment-resistant depression.
Is PTSD Neurodivergent? What the Brain Science Shows
PTSD isn't classified as neurodivergent, but it's tied to real differences in how the brain handles threat. See what scans show, who's at risk, and what helps.
Genetic Testing for Psychiatric Medications: What It Can and Can't Tell You
Pharmacogenomic tests show how your genes may affect some antidepressants, but trial benefits are modest. Learn who testing helps and how to use results safely.
PHQ-9 Depression Screening: How Doctors Actually Use the Score
The PHQ-9 is more than a checklist. Here is how doctors use your score to screen, measure severity, guide treatment decisions, and know when to change your plan.