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Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.

Psychiatrist Answers: Why Your Antidepressant Stops Working Over Time

Your antidepressant worked for months. Now it does not. A psychiatrist explains the clinical phenomenon behind antidepressant tolerance and what happens next.

May 29, 2026Antidepressant ToleranceTachyphylaxisSSRI EffectivenessMedication Management