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The Siggy Blog

Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.

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Wellbutrin vs SSRIs: When Doctors Choose Bupropion First

Bupropion and SSRIs are both first-line antidepressants, but they work differently and suit different patients. Here is the clinical decision that makes a prescriber reach for one over the other.

June 1, 2026Wellbutrin (Bupropion)SSRI vs BupropionDrug EducationAntidepressant ComparisonNDRI