News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
Mirtazapine Withdrawal: Rebound Insomnia, Nausea, and How to Taper
Stopping mirtazapine? Learn why sleep and nausea can flare, how to tell withdrawal from relapse, and how to plan a gradual taper with your prescriber.
Mirtazapine Weight Gain: How Much, How Fast, and What Helps
Mirtazapine raised appetite in 17% of people in trials. See how much weight gain studies show, what dose does and doesn't change, and ways to manage it.
Mirtazapine Dosage: The Sedation Paradox and What Trials Show
Mirtazapine starts at 15 mg and tops out at 45 mg. See why low doses are called more sedating, what the studies actually measured, and how doses get adjusted.
Mirtazapine for Sleep and Appetite: When Sedation Is the Point
Mirtazapine's drowsiness and appetite boost can help depression with insomnia or weight loss. See what trials show, why benefits may fade, and how dosing works.
Mirtazapine for Anxiety: How It Works and Who It Helps
Mirtazapine is not an SSRI. Its mechanism is fundamentally different, and so is the patient it works best for. Here is what the clinical evidence actually shows about mirtazapine for anxiety.