News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
Can You Take Ibuprofen With Zoloft? Bleeding Risk Explained
Can you take ibuprofen with Zoloft? What research shows about SSRI plus NSAID bleeding risk, who is most at risk, warning signs, and safer ways to treat pain.
Serotonin Syndrome Symptoms: Early Signs and Drug Combinations to Avoid
Learn the early signs of serotonin syndrome, which drug combinations carry real risk, from MAOIs to tramadol, and which ones research shows are rarely a problem.
Hydroxyzine and Alcohol: Sedation Risks Explained
Hydroxyzine and alcohol stack up to more sedation than either alone. See what controlled studies found, how long hydroxyzine lasts, and when to get help.
Lithium Toxicity Symptoms: Early Signs and Emergency Red Flags
Know the early signs of lithium toxicity, what pushes levels up, from dehydration to ibuprofen, and which symptoms mean you should call 911 right now.
Celexa vs. Lexapro: Which Is Better for Anxiety and Depression?
Celexa and Lexapro are related SSRIs but differ in FDA approvals, dosing limits, and cardiac safety profile. A prescriber explains the clinical decision between them.
Ozempic and Anxiety: What the Mental Health Research Actually Shows
Can Ozempic cause anxiety or depression? Here's what trials, large cohort studies, and the current label say about semaglutide and your mental health.