News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
FeaturedClinical & Research
The Genetic Factors of Depression: What Your DNA Tells You
Depression is not caused by one broken gene. Here is what twin studies, large genetic studies, and decades of research actually show about DNA and depression risk.
July 6, 2026Genetics of DepressionDepression HeritabilityFamily History Of DepressionDepression Risk Factors
Symptoms & ExperiencesJune 26, 2026
Why Am I Depressed? When There's No Obvious Reason, There's Usually a Quiet One
Feeling depressed with no clear reason? Learn the hidden drivers, from genes and stress to thyroid problems, sleep, and medications, and what to get checked.
Why Am I DepressedDepression TriggersDepression Risk FactorsDepression SymptomsBipolar Misdiagnosis
Conditions & DiagnosesJune 23, 2026
What Causes Depression? What the Science Shows Beyond the Chemical Imbalance
Depression isn't simply low serotonin. See what research shows about genes, early adversity, stress, inflammation, and sleep, and what it means for treatment.
What Causes DepressionGenetics of DepressionDepression Risk FactorsDepression NeuroscienceMajor Depressive Disorder