News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
Brain Fog: The Mental Health Causes Doctors Look For First
Brain fog has causes a clinician can find. Learn how depression, anxiety, ADHD, sleep loss, and medications cloud thinking, and when to get checked.
How Long Does Trintellix Take to Work? Mood vs Focus Timelines
How long Trintellix takes to work: when mood starts to shift, why full effect takes 4 weeks or more, how focus changes separately, and when to reassess.
Trintellix vs Lexapro: What the Evidence Says About Brain Fog
Trintellix vs Lexapro for depression's cognitive symptoms: what the trials show on focus and brain fog, how side effects differ, and when prescribers switch.
Depression and Memory Loss: Why It Happens and How to Cope
Depression can cause real memory and concentration problems, not just low mood. Learn why it happens, how it differs from dementia, and how it gets better.
Trintellix for Depression: What Makes It Different and What the Evidence Shows
Trintellix blocks serotonin reuptake and acts on serotonin receptors directly. Learn how it compares, its real side effect rates, dosing, and who it may suit.
What Does Depression Feel Like? The Parts No One Mentions
Depression often feels like emptiness, exhaustion, fog, or irritability more than sadness. Learn how it shows up in mind and body, and when to get help.