News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
Clonidine for Sleep Can Help Some People, and Stopping It Takes a Plan
Clonidine is used off-label for sleep in ADHD and PTSD. See what the evidence shows, the side effects, and why stopping suddenly can spike blood pressure.
Guanfacine vs Clonidine: Sedation, Duration, and Typical Uses
Guanfacine and clonidine are both alpha-2 agonists for ADHD, but they differ in sedation, how long a dose lasts, and rebound risk. See how they compare.
Clonidine for ADHD: Sleep, Impulsivity, and Add-On Use
Clonidine ER can ease hyperactivity, impulsivity, and bedtime struggles in ADHD, alone or with a stimulant. See the dosing, sleepiness rates, and taper rules.
Clonidine Side Effects and the Rebound Risk of Stopping
Clonidine causes dose-related sedation and dry mouth, but the bigger danger is stopping it abruptly. Here is what causes rebound hypertension and how it is prevented.