News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
FeaturedMedications
Bipolar Depression Treatment: Why Antidepressants Alone Are Risky
Why antidepressants alone can backfire in bipolar depression, and what research shows about quetiapine, lurasidone, cariprazine, and lamotrigine instead.
October 15, 2026Bipolar Depression TreatmentBipolar DisorderMood StabilizersLamotrigineBipolar Misdiagnosis
MedicationsSeptember 25, 2026
Latuda Dosage: Why the 350-Calorie Rule Changes Your Dose
Latuda starts at 20 mg for bipolar depression, but food decides how much you absorb. See the dose ranges and why a 350-calorie meal roughly doubles exposure.
Latuda (Lurasidone)Latuda DosageBipolar Depression TreatmentAntipsychotic Dose ResponseFood-Drug Interactions
Conditions & DiagnosesJune 30, 2026
Bipolar Depression vs. Depression: Why the Difference Lives in Your History
Bipolar depression can look identical to major depression. Learn the history clues that tell them apart and why the difference changes treatment.
Bipolar vs Unipolar DepressionBipolar MisdiagnosisBipolar Depression TreatmentMania SymptomsMajor Depressive Disorder