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The Siggy Blog

Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.

FeaturedMedications

Abilify Weight Gain: Lower Than Most Antipsychotics, but Not Zero

Abilify causes less weight gain than most antipsychotics, but not none. See what short-term trials and year-long data show, who gains more, and what helps.

November 2, 2026Abilify (Aripiprazole)Antipsychotic Weight GainAntipsychotic Side EffectsAdjunctive Depression TreatmentMetabolic Monitoring
MedicationsOctober 22, 2026

Seroquel Weight Gain: How Much and How to Monitor

How much weight people gain on Seroquel, why the first month matters, which blood tests to get and when, and what research shows helps if the scale climbs.

Seroquel (Quetiapine)Seroquel Weight GainMetabolic MonitoringAntipsychotic Side Effects
MedicationsOctober 15, 2026

Risperidone Side Effects: Prolactin, Weight, and Movement Effects

Risperidone raises prolactin more than most antipsychotics and can affect weight and movement. Learn what to watch for and the monitoring schedule to expect.

RisperidoneAntipsychotic Side EffectsHyperprolactinemiaTardive Dyskinesia
MedicationsOctober 15, 2026

Tardive Dyskinesia Symptoms: Early Signs on Antipsychotics

Learn the early signs of tardive dyskinesia, who is most at risk on antipsychotics, how it's monitored, and what treatments can help.

Tardive DyskinesiaAntipsychotic Side EffectsAntipsychoticsVMAT2 InhibitorsMedication-Induced Movement Disorders
MedicationsSeptember 30, 2026

Abilify Side Effects: Akathisia, Weight, and Impulse Control

Abilify side effects range from restlessness and weight gain to rare impulse-control urges. See what the FDA boxed warnings mean and which signs need a call.

Abilify (Aripiprazole)Abilify Side EffectsAkathisiaAntipsychotic Side EffectsAntidepressant Augmentation
MedicationsSeptember 30, 2026

Latuda Side Effects: Akathisia, Nausea, and the Food Rule

Latuda's most common side effects are restlessness, nausea, and sleepiness. See how dose and food shape them, what helps, and how it compares on weight gain.

Latuda (Lurasidone)AkathisiaAntipsychotic Side EffectsBipolar Medication Side Effects
MedicationsSeptember 30, 2026

Rexulti Side Effects: What to Expect as a Depression Add-On

Rexulti side effects center on restlessness and weight gain, which can rise with dose. See the label data, how Rexulti compares with Abilify, and what to watch.

Rexulti (Brexpiprazole)Rexulti Side EffectsAkathisiaAntipsychotic Side EffectsAntidepressant Augmentation
MedicationsSeptember 24, 2026

How Long Does Abilify Take to Work? Add-On vs. Standalone

Abilify can act within days for mania and within one to two weeks as an antidepressant add-on. See what the trials show about timing, dosing, and what to track.

Abilify (Aripiprazole)Abilify TimelineAntidepressant AugmentationAntipsychotic Side Effects
MedicationsSeptember 17, 2026

Vraylar Side Effects and Akathisia: A Timeline Guide

Vraylar (cariprazine) causes akathisia in a meaningful share of patients. Here is the realistic timeline, why it happens, and what prescribers adjust first.

Vraylar (Cariprazine)Vraylar Side EffectsAkathisiaAntipsychotic Side Effects