News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
Signs Your Antidepressant Dose Is Too Low and What to Track
Feeling a little better but not well? Learn the signs your antidepressant dose may be too low, what partial response looks like, and what to track first.
What Is Treatment-Resistant Depression? How to Tell Whether Your Last Two Antidepressants Really Counted
Treatment-resistant depression means two adequate antidepressant trials didn't work. Learn how to audit past trials, the odds at each step, and what comes next.
Antidepressant Not Working After 8 Weeks: A Doctor-Reviewed Decision Path
Eight weeks on an antidepressant with no response is a clinical signal, not a dead end. Here is the doctor-reviewed decision path for what happens next.
Antidepressant Not Working? 3 Patterns to Check Before You Switch
Before switching antidepressants, three clinical patterns explain most cases of apparent treatment failure. Here is how to check each one before making any changes.