News & Research
The Siggy Blog
Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.
FeaturedMedications
Amitriptyline Side Effects: Why Dose and Age Change the Whole Picture
Amitriptyline side effects depend heavily on dose and age. Learn about sedation, dry mouth, heart rhythm cautions, and why older adults face extra risks.
November 2, 2026AmitriptylineTricyclic AntidepressantsAnticholinergic Side EffectsAntidepressant Side EffectsMedications in Older Adults
MedicationsOctober 15, 2026
Tricyclic Antidepressants: What They Are and When They Are Still Used
How tricyclic antidepressants work, why SSRIs replaced them as a first choice, where they still help with pain, sleep, and OCD, and how to use them safely.
Tricyclic AntidepressantsAntidepressant ClassesAnticholinergic Side EffectsAntidepressant Side EffectsNortriptyline
MedicationsOctober 6, 2026
Nortriptyline Side Effects, Heart Checks, and Blood Levels
Nortriptyline side effects explained: dry mouth and other anticholinergic effects, how it affects your heart, why blood levels matter, and when to call.
NortriptylineTricyclic AntidepressantsAnticholinergic Side EffectsMedication MonitoringPharmacogenomics